San Diego: America’s Wildest City explores the stunning biodiversity and resilience of San Diego’s natural world, from its coastlines to deserts. The documentary showcases how wildlife adapts to human-induced changes, such as dammed rivers, urban parks, and sprawling suburbs. Key moments include Western grebes’ mating rituals, squirrel colonies thriving in parks, and the challenges animals face, like border walls and water scarcity. It highlights dramatic scenes of marine life, like orcas hunting dolphins and grunion spawning. Amid challenges, species like hummingbirds and bobcats coexist with humans. The film underscores the need for responsible stewardship to preserve San Diego’s unique natural heritage.